{"id":13386,"date":"2024-10-21T14:55:31","date_gmt":"2024-10-21T14:55:31","guid":{"rendered":"https:\/\/www.chromagar.com\/?p=13386"},"modified":"2024-10-22T10:39:24","modified_gmt":"2024-10-22T10:39:24","slug":"the-threat-of-carbapenem-resistant-enterobacteriaceae-2","status":"publish","type":"post","link":"https:\/\/www.chromagar.com\/en\/the-threat-of-carbapenem-resistant-enterobacteriaceae-2\/","title":{"rendered":"The threat of Carbapenem-Resistant Enterobacteriaceae"},"content":{"rendered":"<div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-30 vce-row-equal-height vce-row-content--top\" id=\"el-12b4eecd\" data-vce-do-apply=\"all el-12b4eecd\"><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-auto vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-c2c9cd18\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-c2c9cd18\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-c2c9cd18\"><div class=\"vce-single-image-container vce-single-image--align-left\"><div class=\"vce vce-single-image-wrapper\" id=\"el-1b47a0eb\" data-vce-do-apply=\"all el-1b47a0eb\"><figure><div class=\"vce-single-image-inner vce-single-image--absolute\" style=\"padding-bottom: 71.2891%; width: 1024px;\"><img decoding=\"async\" loading=\"lazy\" class=\"vce-single-image vcv-lozad\" data-src=\"https:\/\/www.chromagar.com\/wp-content\/uploads\/2024\/10\/CHROMagar.com-POST-IMAGE-CHROMagar-mSuperCARBA.png\" width=\"1024\" height=\"730\" src=\"\" data-img-src=\"https:\/\/www.chromagar.com\/wp-content\/uploads\/2024\/10\/CHROMagar.com-POST-IMAGE-CHROMagar-mSuperCARBA.png\" alt=\"\" title=\"CHROMagar.com - POST IMAGE - CHROMagar mSuperCARBA\" \/><noscript>\r\n        <img decoding=\"async\" loading=\"lazy\" class=\"vce-single-image\" src=\"https:\/\/www.chromagar.com\/wp-content\/uploads\/2024\/10\/CHROMagar.com-POST-IMAGE-CHROMagar-mSuperCARBA.png\" width=\"1024\" height=\"730\" alt=\"\" title=\"CHROMagar.com - POST IMAGE - CHROMagar mSuperCARBA\" \/>\r\n      <\/noscript><\/div><figcaption hidden=\"\"><\/figcaption><\/figure><\/div><\/div><\/div><\/div><\/div><div class=\"vce-col vce-col--md-auto vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last\" id=\"el-aada0f38\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-aada0f38\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-aada0f38\"><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-d62c90e8\" data-vce-do-apply=\"all el-d62c90e8\"><h2 style=\"line-height: 1.5;\"><span style=\"font-size: 12pt;\">CRE infections are becoming a major concern in healthcare settings worldwide.<br><br>This family of bacteria is notorious for its resistance to almost all available antibiotics, significantly limiting treatment options. The bacteria\u2019s ability to spread rapidly poses a serious risk, especially when outbreaks occur, adding to both patient suffering and the financial burden on healthcare systems.<br>The mortality rates linked to CRE infections are also alarming.<br><br>In severe cases, the mortality rate can reach 75%. For patients suffering from CRE bloodstream infections, the mortality rate is observed to be around 50%. These statistics underscore the critical nature of these infections and the need for better treatment options and infection control strategies.<\/span><\/h2><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-30 vce-row-equal-height vce-row-content--top\" id=\"el-619cfa09\" data-vce-do-apply=\"all el-619cfa09\"><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-auto vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-49ca6252\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-49ca6252\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-49ca6252\"><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-d1fe865f\" data-vce-do-apply=\"all el-d1fe865f\"><h2 style=\"line-height: 1.5;\"><span style=\"font-size: 12pt;\">In addition, CRE infections place a heavy financial strain on healthcare systems:<br><br>\ud83c\uddfa\ud83c\uddf8 In the United States, the estimated annual healthcare costs associated with CRE infections amount to approximately $130 million.<br>\ud83c\uddeb\ud83c\uddf7 In France, over a two-year period, the cost for treating 16 patients carrying carbapenemase-producing CRE reached over \u20ac640,000.<br>\ud83c\uddec\ud83c\udde7 In the United Kingdom, similarly, a CRE outbreak in five hospitals over a span of 10 months led to expenses exceeding \u20ac1 million.<br>&nbsp;<br><\/span><\/h2><br><h2><span style=\"font-size: 20pt;\">How to address the growing threat of CRE infections?<\/span><\/h2><br>&nbsp;<br><h2 style=\"line-height: 1.5;\"><span style=\"font-size: 12pt;\">CRE infections are not only a serious health risk due to their high mortality rates but also pose a significant economic challenge to healthcare systems. As the threat of these antibiotic-resistant bacteria grows, it is imperative to focus on prevention and rapid detection to support easing their impact on both patients and healthcare facilities.<\/span><\/h2><br><h2><span style=\"font-size: 20pt;\">Discover CHROMagar\u2122 mSuperCARBA\u2122<\/span><\/h2><br>&nbsp;<br><h2><span style=\"font-size: 12pt;\"> CHROMagar\u2122 mSuperCARBA\u2122 is designed for detection and isolation ofCarbapenem-Resistant<\/span> <span style=\"font-size:12pt; font-style: italic;\">Enterobacteriaceae<\/span><span style=\"font-size: 12pt;\"> (CRE).<\/span><\/h2><br><h2 style=\"line-height: 1.5;\"><span style=\"font-size: 12pt;\">Its main advantages are:<\/span><\/h2><br><ul style=\"list-style-type: circle;\"><br> \t<li><h2 style=\"line-height: 1.5;\"><span style=\"font-size: 12pt;\"> \ud83d\udd2c Differentiation of most CRO*:<br>Designed to detect a wide range of carbapenemase producers (KPC, NDM, VIM, IMP, OXA\u2026). It can even detect weakly expressed carbapenemases like OXA-244 and OXA-48.<br><\/span><\/h2><br><\/li><br> \t<li><h2 style=\"line-height: 1.5;\"><span style=\"font-size: 12pt;\"> \ud83c\udfaf Highly selective and specific:<br>The medium inhibits not only beta-lactam susceptible bacteria but also most ESBL and AmpC hyperproducers.<br><\/span><\/h2><br><\/li><br> \t<li><h2 style=\"line-height: 1.5;\"><span style=\"font-size: 12pt;\"> \ud83d\udd0d Impressive limit of detection:<br>It possesses an impressive limit of detection of 10 CFU\/ml.<br><\/span><\/h2><br><\/li><br> \t<li><h2 style=\"line-height: 1.5;\"><span style=\"font-size: 12pt;\"> \u23f2\ufe0f Fast results<br>Can be interpreted after 18-24h of aerobic incubation at 35-37\u00b0C.<br><\/span><\/h2><br><\/li><br><\/ul><br><h2 style=\"line-height: 1.5;\"><span style=\"font-size: 12pt;\">You can <a href=\"https:\/\/www.chromagar.com\/product\/chromagar-msupercarba\/\">find here<\/a> \ud83d\udc48 all the technical documents and information about CHROMagar\u2122 mSuperCARBA\u2122<br>Here to support you<br>Do you have any questions or want to have more details? Don't hesitate to <a href=\"https:\/\/www.chromagar.com\/contact\/\">contact us here<\/a> \ud83d\udc48<br>Our team will delighted to reach out to you in a brief time \ud83d\udc9c<\/span><\/h2><br><br><br>The CHROMagar Team<br><br><br><h2 style=\"line-height: 1.5;\"><span style=\"font-size: 9pt;\">* CRO: Carbapenem-Resistant organism.<br>1. Carbapenem-resistant Enterobacteriaceae \u2013 second update, 26 September 2019, ECDC.<br>2. CDC, 2019 Antibiotic Resistance Threats Report, Carbapenem-resistant Enterobacteriaceae (CRE) MAR 25\/2024. https:\/\/www.cdc.gov\/antimicrobial-resistance\/media\/pdfs\/cre-508.pdf<br>3. Daroukh A, Delaunay C, Bigot S, et al. Characteristics and costs of carbapenemase-producing enterobacteria carriers (2012\/2013). Med Mal Infect. 2014;44(7):321-326. doi:10. 1016\/j.medmal.2014.06.004<br>4. Otter JA, Burgess P, Davies F, et al. Counting the cost of an outbreak of carbapenemase-producing Enterobacteriaceae: an economic evaluation from a hospital perspective. Clin Microbiol Infect. 2017;23(3):188-196. doi:10.1016\/j.cmi.2016.10.005<br>5. Garcia-Fernandez et al., 2017. Diagn. Micr. Infect. Dis. <\/span><\/h2><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>CRE infections are becoming a major concern in healthcare settings worldwide.This family of bacteria is notorious for its resistance to almost all available antibiotics, significantly limiting treatment options. The bacteria\u2019s ability to spread rapidly poses a serious risk, especially when outbreaks occur, adding to both patient suffering and the financial burden on healthcare systems.The mortality [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":13376,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[18],"tags":[],"_links":{"self":[{"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/posts\/13386"}],"collection":[{"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/comments?post=13386"}],"version-history":[{"count":13,"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/posts\/13386\/revisions"}],"predecessor-version":[{"id":13399,"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/posts\/13386\/revisions\/13399"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/media\/13376"}],"wp:attachment":[{"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/media?parent=13386"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/categories?post=13386"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.chromagar.com\/en\/wp-json\/wp\/v2\/tags?post=13386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}