Clinical Microbiology


CHROMagar™ mSuperCARBA™

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Packaging / Colonies appearance

For Detection of gram-negative bacteria
with a reduced susceptibility
to most of the carbapenem agents.

Typical Appearance of microorganisms

CPE E.coli → dark pink to reddish
CPE Coliforms → metallic blue
CPE Pseudomonas → translucent, +/- natural pigmentation cream to green
CPE Acinetobacter → Cream
Other Gram negative CPE → colourless, natural pigmentation
Non-CPE E.coli/ Coliforms → inhibited
Other Gram negative non-CPE → inhibited

Order References 

Please use these references when
contacting your local distributor:

5000ml.............. SC172
25L.................... SC173-25 
To download the certificate of analysis, please indicate your lot number below :


Medium Description

  1. HIGHLY SENSITIVE: Most Carbapenemases (including OXA-48 and OXA-48 like) detected after overnight incubation. 


  3. HIGHLY SELECTIVE AND SPECIFIC: Not only beta-lactam susceptible bacteria are inhibited, but also most of the ESBL and AmpC hyperproducers are inhibited, rendering the tool very specific for carbapenemase-producing bacteria.

Media Description 

Please refer to our notice and Material Safety data sheet for complete information about the medium. 
CHROMagar™, Rambach™, AquaCHROM™ are trademarks created by Dr. A. Rambach.
                                                                                                     Last Update: 26-Oct-2017

CRE Epidemiologic Issues

CDC: «Carbapenem-resistant Enterobacteriaceae (CRE) are usually resistant to all β-lactam agents as well as most other classes of antimicrobial agents. The treatment options for patients infected with CRE are very limited. Healthcare-associated outbreaks of CRE have been reported. Patients colonized with CRE are thought to be a source of transmission in the healthcare setting. Identifying patients who are colonized with CRE and placing these patients in isolation precautions may be an important step in preventing transmission».

CHROMagar launched in 2007 the first chromogenic medium for the detection of carbapenem-resistant bacteria, particularly targeting KPC-enzymes. Since then, many other carbapenemases have been spreading around the world and therefore there was a need to address today the difficult detection of low level carbapemases.

Alain Rambach and Patrice Nordmann have joined their efforts to develop a highly sensitive chromogenic medium, CHROMagarTM mSuperCARBATM, the new generation of chromogenic media that reaches unprecedented performances: detection of a large variety of carbapenemases KPC, NDM, VIM, IMP, OXA…with an impressive limit of detection (10 CFU/ml) even for weakly expressed carbapenemases like OXA-48, while maintaining a high level of selectivity.


CHROMagar mSuperCARBA performance in carbapenem-resistant Enterobacteriaceae isolates characterized at molecular level and routine surveillance rectal swab specimens


García-Fernández S., Hernández-García M., Valverde A., Ruiz-Garbajosa P., Morosini MI., Cantón R.- Servicio de Microbiología, Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain

Validation of Colorex™ ESBL/mSuperCARBA™ bi-plate on WASP®/WASPLab® to screen for ESBL and CPE


M. Gaskin, D.Yamamura, J. Korver Hamilton Regional Laboratory Medicine Program ECCMID Madrid April 2018

Dépistage du portage digestif d`entérobactéries productrices de carbapénemases (EPC) dans l Algérois durant l année 2016


S. Hamrouche (1), S. Oukid (2), Y. Boutaba (1), S. Sadat (1), R. Belouni (2), M.N. Ouar-Korichi (1) - (1) Institut Pasteur d`Algérie, Alger, ALGÉRIE; (2) Clinique Hassiba Ben Bouali - CHU Blida, Blida, ALGÉRIE
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