Clinical Microbiology

 

CHROMagar™ Candida


Click on the picture for
Packaging / Colonies appearance
 





For isolation and differentiation
of major clinical-significant Candida species.


Typical Appearance of microrganisms

Candida albicans → green
Candida tropicalis → metallic blue
Candida krusei → pink, fuzzy
Other species → white to mauve

Order References 

Please use these references when
contacting your local distributor:

1000ml..........CA220
5000ml..........CA222
25L...............CA223-25
Bulk on request


To download the certificate of analysis, please indicate your lot number below :
 

 
 

Medium Performance


  1. High Contrast: intense colony colouration helping to differentiate species.

  2. 36-48 h incubation at 35 °C or higher.

  3. Panoramic view of the Candida population mix with the ability to detect major species but also the presence of minor populations. 

  4. Powerful tool: displays high specificity and sensitivity for 3 of the major Candida species at a time.
    Specificity and sensitivity:
    Candida albicans  → Exceed 99%* 
    Candida tropicalis → Exceed 99%*
    Candida krusei     → Exceed 99%*
    *Specificity and sensitivity from scientific study: “CHROMagar Candida, a new differential isolation medium for the presumptive identification of clinically important Candida species.” Odds F. et al 1994, Journal of Clinical Microbiology, 32 : 1923-1929.

  5. Less workload: with traditional media such as Sabouraud agar, identification of mixed cultures is difficult, whereas CHROMagar Candida, just by the colour of the colony, will instantly differentiate various Candida species. 

  6. Facilitates the choice of appropriate and optimised antifungal therapies.



Medium Description




Gain flexibility using powder rather than ready to use plates: Use the entire pack, or if there is a need for a smaller number of plates, just a portion. If kept under appropriate storage temperature, CHROMagar Candida has a 3 years shelf of life. This flexibility is essential to avoid the waste resulting from expired-unused plates. No need of supplements: all components are included in the powder. 


CE marked Product.
Please refer to our IFU and Material Safety data sheet for complete information about the medium. CHROMagar™, Rambach™, AquaCHROM™ are trademarks created by Dr. A. Rambach.
Last Update: 19-Nov-2010

Focus on Candida Species


Commensal yeasts usually present in the human mouth, gastro-intestinal tract, vagina and skin, Candida species can also be opportunistic pathogens. They are one of the most common causes of fungal infections.

Two main diseases (called candidiasis or candidosis) are described:
  • Mucocutaneous Candidiasis: Usually of minor consequence, these skin or mucosal infections can, however, become severe in immuno-compromised patients such as HIV-positive individuals.
  • Systemic Candidiasis: This nosocomial infection occurrs in patients whose resistance to infection is drastically lowered as a result of immunosuppression, major surgery, trauma, etc.

Candida Epidemiologic Issues


Perhaps as a result of progress in medical therapy with a related decrease in patient resistance and increase in the number of susceptible hosts, the incidence of bloodstream Candida infections rose through the 1990s but has stabilised in recent years.

More commonly, Candida species are involved in superficial oropharyngeal and urogenital infections. T
“Early diagnosis is essential for early effective management of the patients.” WHO Guidelines on Standard Operating Procedures for Laboratory Diagnosis of HIV-Opportunistic Infections) 

Although C. albicans remains the major species involved, other types such as C. tropicalis, C. krusei or C.glabrata have increased proportionately as new antifungal agents have worked very effectively against C. albicans.

 

Application of CHROMagar Candida for rapid screening of clinical specimens for Candida albicans, Candida tropicalis, Candida krusei, and Candida (Torulopsis) glabrata.

1996

Pfaller M.A. et al.
1996. Journal of Clinical Microbiology, 34 : 58-61
PUBLICATION

Use of CHROMagar Candida medium for isolation of yeasts from dental samples.

1995

Beighton D. et al.
1995. Journal of Clinical Microbiology,33:3025-3027.

 

PUBLICATION

CHROMagar Candida, a new differential isolation medium for the presumptive identification of clinically important Candida species

1994

Odds F. et al.
1994, Journal of Clinical Microbiology, 32 : 1923-1929.

PUBLICATION
 
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